TY - JOUR AU - Shekhar Gopalrao Uike, PY - 2019/01/19 Y2 - 2024/03/29 TI - STUDY OF INDIVIDUAL’S PRAKRITI AND GENE POLYMORPHISM CORRELATION OF P2Y12 GENE JF - AYUSHDHARA JA - Ayushdhara VL - 5 IS - 5 SE - DO - UR - https://ayushdhara.in/index.php/ayushdhara/article/view/415 SP - 1862-1868 AB - <p>Ayurveda is a science of self understanding. It is understood by its own unique nature or constitution i.e. <em>Prakruti</em>. Ayurveda believes that the individual’s constitution (<em>Prakruti</em>) is framed at the time of conception as a genetic code or predominant <em>Panchamahabhautic dosha</em>. Ayurveda classifies human beings into three distinct types: <em>Vata, Pitta </em>and <em>Kapha</em> with multiple subtypes. <em>Rakta</em> is said to be the 4<sup>th</sup> <em>Dosha</em>, i.e. it has the importance as that of <em>Tridosha</em>. All <em>Dhatus</em> are dependent for their nourishment on <em>Raktadhatu</em>. Chakrapani explains different shades of <em>Raktadhatu</em> according to different <em>Prakriti</em>. So there is close relation between <em>Raktadhatu</em> and <em>Prakriti</em>. <em>Doshas</em> which are responsible for <em>Prakriti</em> remain constant and they do not change until death. Genetic constitution is identical and unique for every person, the same as <em>Prakriti</em>. Every gene performs a specific function. So <em>Prakriti</em> can be correlated with genetics whether there is any particular genetic pattern for the particular <em>Prakriti</em> with the help of a tool like Single Nucleotide Polymorphism. P2Y12, the receptor present on the platelet surface, initiates platelet aggregation. To analyse polymorphism in the P2Y12 gene, in exhibiting platelet aggregative response, in correlation with <em>Prakriti</em>.</p><p>&nbsp;</p> ER -