AYUSHDHARA is an international peer reviewed Bi-monthly open access journal publishing print and online versions. AYUSHDHARA focused towards the publication of current research work carried out under Ayurveda, Yoga, Unani, Siddha and Homeopathy, Allopathy systems of medicine and Pharmaceutical Sciences. AYUSHDHARA title approved for print version by Office of the Registrar of Newspapers for India, Ministry of Information And Broadcasting, New Delhi (RNI Registration No: TELENG/2014/60297). AYUSHDHARA an emerging academic journal in the field of Ayurveda, Yoga, Unani, Siddha and Homeopathy which deals with all facets of the field of research work conducting various institutes and researches. This journal motive and aim is to create awareness, re-shaping the knowledge already created and challenge the existing theories related to the field of Academic Research in any discipline in AYUSH Systems strive to set the highest standards for superiority in everything we do in content, style and aesthetics of presentation, in editorial performance at every level, in transparency and accessibility to the scientific community and public, and in educational value. The journal aims to publish novel research being conducted and carried out of academic and industry authors, researchers, and readers in a medium customized for the discovery, integration, and application of research. We are inviting professors, researchers, professionals, academicians and research scholars to submit their novel and conjectural ideas in the domain of AYSUH Systems in the shape of (1). Original Research Articles (2). Review articles (3). Book Reviews (4). Short Communications/ Research Letter (5). Case Report (6). Letter to the Editor/Correspondence. Ayurved Samhita & Siddhanta (Ayurvedic Compendia & Basic Principles), Rachana Sharir (Anatomy), Kriya sharir (Physiology), Dravyaguna Vigyan (Materia Medica & Pharmacology), Rasashastra (Ayurvedic Metals & Minerals/Iatrochemistry) Bhaishajya Kalpana (Pharmaceuticals Science), Agadtantra & Vidhi Vaidyaka (Toxicology & Forensic Medicine), Svasthavritta (Preventive, Social Medicine & Yoga), Roganidana & Vikriti Vigyan (Pathology & Diagnostic Procedure), Kayachikitsa (General Medicine), Manovigyan & Manasroga (Psychiatry), Rasayan & Vajikaran (Rejuvenation & Aphrodisia), Panchakarma (Five Bio-cleansing Procedures), Prasuti & Stri Roga (Gynecology & Obstetrics), Kaumarbhritya-Balaroga (Pediatrics), Shalyatantra (General Surgery), Shalakyatantra (Otorhinolaryngology/ENT & Ophthalmology). Research articles on above the subjects using current scientific knowledge viz., Ethnobotany, Phytochemistry, Drug Standardization, Quality control, Good Laboratory Practices (GLP), Pharmacology, Preclinical research, Clinical research, Good Clinical Practices (GCP), Pharmacovigilance. Studies on Literary, Basic and Fundamental research, Preventive and Promotive Healthcare, Local Health Traditions, etc. which provide the leads to the original research are also acceptable. Pharmaceutical Sciences Further, studies on Herbal/Natural products in the area of Pharmaceutical Chemistry, Pharmacognosy and Phytochemistry, Drug delivery systems, Pharmacology, Pharmaceutical analysis, Herbal/Ayurvedic Pharmacy practice, Bioinformatics and Pharmaceutical biosciences.
Asrigdara (Menorrhagia): A Comparative Study Between Ayurvedic and Modern Perspectives
Asrigdara, a condition described in Ayurveda under Raktapradara Roga, closely resembles menorrhagia described in modern gynaecology. This condition not only affects a woman's physiological balance but also impairs her mental, social, and reproductive health. Both conditions manifest as excessive or prolonged uterine bleeding independent of or associated with menstrual cycles. The condition leads to anemia, Fatigue and impaired quality of life. This article aims to correlate the Ayurvedic understanding of Asrigdara with modern concepts of menorrhagia, exploring their etiopathogenesis, clinical presentation, and management approaches. The Ayurvedic viewpoint underscores a holistic understanding based on Dosha-Dhatu-Mala interaction and Srotodushti, whereas modern medicine relies on evidence-based diagnostic tools, including ultrasonography, hormonal assays, and endometrial evaluation. Similarly, treatment in Ayurveda focuses on restoring balance through Samana and Sodhana therapies, herbal formulations such as Asoka, Lodhra, Musta, Nagakesara, and lifestyle modifications rooted in Dinacharya and Ritucharya. Modern therapy, in contrast, includes NSAIDs, antifibrinolytics, hormonal therapy, and surgical interventions like endometrial ablation or Hysterectomy depending on severity and underlying cause. A comprehensive review of classical Ayurvedic texts and contemporary gynaecological literature was conducted. Findings reveal that Asrigdara primarily results from vitiation of Pitta and Rakta and derangement of Artavavaha Srotas, while menorrhagia is due to hormonal imbalance, uterine pathology or systemic disorders. The study concludes that integrating Ayurvedic and modern approaches offers a holistic management strategy for menorrhagia.
Asrigdara, Artavavaha Srotas, Pitta, Rakta, Ayurveda, Raktapradara Roga.
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Srotas: The Vital Channels of Life - An Ayurvedic and Modern Perspective
In Ayurveda, Srotas are considered the fundamental channels through which various bodily functions occur, including transport of nutrients, waste products, and vital energies. Srotas forms the foundational framework of Ayurvedic physiology, representing the intricate network of channels responsible for circulation of Dosha, Dhatu, and Mala. Ancient texts, especially those of Charaka and Sushruta, emphasize that the integrity of Srotas is essential for the sustenance of life, Homeostasis, and optimal physiological functioning. In modern physiological networks such as the circulatory system, lymphatic channels, neuronal pathways, interstitial fluid channels, cellular and endocrine communication closely correlate with the Ayurvedic description of Srotas. For example, Pranavaha Srotas parallels the respiratory and oxygen-transport system; Rasavaha and Raktavaha resemble the cardiovascular and microcirculatory networks. Pathological alterations of Srotas (Srotodushti)- including obstruction, dilatation, narrowing, rupture, and perversion of flow are explained in Ayurveda through mechanisms such as Avarana, Sanga, Vimargagamana, Ati pravritti, and Srotoviddha. These can be meaningfully interpreted in modern terms as inflammation, microvascular damage, fibrosis, metabolic derangements, oxidative injury, endothelial dysfunction, and neuro-humoral imbalance. The causal factors of Srotas derangement such as improper diet, faulty lifestyle, trauma, stress, and environmental toxins closely parallel modern risk factors like sedentary behaviour, processed food consumption, pollution etc. This article explores the classical concept of Srotas as described in Ayurvedic texts, their types, importance in health and disease, and attempts to correlate them with modern anatomical and physiological systems. Such a comparative understanding may help in better diagnosis and treatment, especially in the field of preventive medicine and chronic disease management.
Ayurveda, Srotas, Srotodushti, Srotoviddha.
Management of Pilonidal Sinus with Chedana Karma and Apamarga Kshara Pratisarana
A Pilonidal sinus (also called as pilonidal cyst, pilonidal disease, or sacrococcygeal fistula) is a small tunnel or tract that forms under the skin, usually near the top of buttocks (in the natal cleft, just above the tailbone). It often results from ingrown hairs, which lead to a cyst or abscess forming under the skin. Male gender is more affected than females with a 4:1 preponderance. Obesity, friction or prolonged sitting, excessive body hair, poor hygiene, young age is some of its risk factors. Acharya Sushruta in Nidana Sthana 10th chapter has described Nadi Vrana where one of its sub types, Shalyaja Nadi Vrana resembles in cause, pathology and clinical symptoms to pilonidal sinus. Chedana karma along with the removal of Shalya, that is, hair tuft is a gold standard for the management of the disease. A 26 years old male patient came to Shalya OPD with complaints of swelling, pain and blood mixed pus discharge from the wound present in sacrococcygeal region for last 2 months. The case was managed successfully with Chedana karma followed by Apamarga kshara Pratisarana and within 2 months, the wound was healed completely.
A Randomized Controlled Trial to Evaluate the Antimicrobial Effect of Petroleum Ether Extract of Arkadigana for Surgical Site Preparation with special reference to Low Anal Fistula
Ayurveda, the ancient Indian medical science, provides extensive guidance on wound management Vrana Chikitsa. Sushruta Samhita, considered the foundational text of Ayurvedic surgery, outlines principles of Purvakarma, Pradhana Karma, and Paschat Karma in operative procedures. Various groups of herbs Ganas described under Dravyasangraha Niyama Adhyaya are indicated for Vrana Shodhana wound cleansing and may be used for skin preparation. Ayurvedic literature also mentions several lotions and chemical formulations later validated as potent antimicrobial agents. Although detailed descriptions of surgical site preparation are not explicitly stated in Sushruta Samhita, this step is implied under Purvakarma and aligns with modern surgical practices. Arkadigana is a unique herbal formulation described in Ayurveda with potent antiseptic, antimicrobial, and antifungal properties. Topical application of Arkadigana is considered safe and beneficial in promoting wound hygiene and reducing microbial contamination. Present study evaluates the antimicrobial effect of petroleum ether extract of Arkadigana for surgical site preparation with special reference to low anal fistula.
Antimicrobial effect, Petroleum ether extract of Arkadigana, Surgical site infection
A Comprehensive Review on Medoroga: Ayurvedic Perspectives and Principles
Medoroga is a defined as the Vyadhi that is pertaining to the Medodhathu. Medodhathu is one among the Saptha dhathu and its imbalance Vridhi and Kshaya which can cause many diseases. In the Vedic period, various synonyms can be seen in the Vedic literatures like Rigveda and Adharvaveda. In the Samhitha period, the Brihathrayees are the classical text. The Charakacharya explained Sthaulya as one of the Vyadhi accused due to Medovridhi. He explained it in the Sutrasthana Ashtaunindhithiya adhyaya. In Susrutha Samhitha, the Medoroga, Sthoulya karana explained as Rasa nimitha. Ashtanga Samgraha, detailed Medoroga, as Sthoulya and the Karana for Sthoulya is given as Ama. In Ashtanga Hridaya Sutrasthana, Dwividhopakraminiya adhyaya, Medo roga is explained as Sthoulya and it comes under the Langhanarha. The treatment of Medoroga, is mainly the Amaharathwa, Dhatwagni Deepana, Srothosodana. The medicines having Deepana pachana srothosodana lekhana can be administered for those who are suffering from Medoroga. Internal as well external therapy also plays a vital role in managing Medoroga. Rasayana also plays remarkable role in treating Medo roga. In this review article, mainly focusing on the Medoroga, Nidana panchak, Chikitsa that can be administered in the treatment of Medoroga.
Medoroga, Sthoulya, Nidana Panchaka, Chikitsa, Rasayana
From Pain to Power: Efficacy of Panchakarma in Vataja Gridhrasi with Padabhramsha
Gridhrasi is a painful neurological disorder characterized by radiating pain, stiffness, and impaired mobility, often correlated with lumbar radiculopathy in contemporary terms. Padabhramsha (foot drop) represents a serious complication arising from aggravated Vata dosha, often triggered by trauma or excessive exertion. This case report presents a 53-year-old female patient with low back pain radiating to the right lower limb, associated with foot drop, following trauma and physical strain. She was also a known case of Type 2 Diabetes Mellitus and hypothyroidism. A comprehensive Panchakarma protocol was designed, including Sarvanga Abhyanga, Parisheka, Shashtikashali Pinda Sweda, dry cupping, and Mustadi Yapana Basti administered in Kala Basti pattern. Treatment outcomes were assessed using clinical parameters such as muscle strength, gait improvement, and SLR test. Significant improvements were noted in pain relief, muscle power (Tibialis anterior and EHL from 1/5 to 2/5), and mobility (step count improved from 8 to 12 steps in 10 seconds). This case highlights the potential of Brimhana Chikitsa and classical Panchakarma therapies in managing Vataja Gridhrasi with Padabhramsha, even in the presence of metabolic comorbidities. Early Ayurvedic intervention, when tailored to the individual Samprapti, can play a pivotal role in functional recovery and quality of life enhancement.
Gridhrasi, foot drop, Panchakarma, Shashtikashali Pinda Sweda, Mustadi Yapana Basti
A Case Study on Ayurvedic Management of Bahya (Pada) Vidradhi
Bahya Vidradhi, particularly Pada Vidradhi, refers to an external abscess characterized by inflammatory swelling, pain, and pus formation. This case study presents a 67-year-old diabetic male with swelling and pain below the left knee, diagnosed as Bahya Pada Vidradhi. The patient was treated using a holistic Ayurvedic approach, including internal medications (Triphala Guggulu, Gandhaka Rasayana, Gokshuradi Guggulu, Punarnava Mandura, and Swarasas), along with aspiration and surgical intervention (incision and drainage). Over 30 days, significant clinical improvement was observed- pain reduced from VAS 8 to 2, swelling subsided, and pus was drained successfully. The site healed with a fibrous scar, and no adverse effects were reported. This outcome supports the effectiveness of Ayurvedic management in treating abscesses, particularly when conventional therapies pose risks or limitations. The case highlights the relevance of classical Ayurvedic principles in modern clinical practice.
Bahya Vidradhi, Pada Vidradhi, Abscess, Triphala Guggulu, Gandhaka Rasayana, Ayurveda
Effect of Putrajeevakadi Yoga on Dhathukshayajanya Bandhya (Secondary Infertility) due to Low AMH
Secondary infertility associated with diminished Anti-Mullerian Hormone (AMH) levels is predominantly linked to endocrine dysfunction. Elevated Follicle Stimulating Hormone (FSH), reduced AMH, and a low Antral Follicle Count (AFC) collectively compromise ovarian reserve, resulting in pregnancy rates below 5% and miscarriage rates exceeding 75%. AMH, secreted by granulosa cells of preantral and antral follicles, is a well-established biomarker for evaluating ovarian reserve and predicting response to controlled ovarian stimulation due to its strong correlation with follicular quantity and recruitment. Women undergoing in vitro fertilization (IVF) with low AMH levels often experience poor outcomes, making donor egg IVF the predominant option. Ayurveda offers a comprehensive and individualized approach to managing Vandhyatva (infertility), focusing on restoring systemic equilibrium, enhancing oocyte quality, and activating the body's intrinsic healing mechanisms. This case study presents a 35-year-old woman with secondary infertility and markedly low AMH levels who was successfully treated with Putrajeevakadi Yoga Ksheerpaka. The intervention resulted in natural conception, highlighting the therapeutic potential of Ayurvedic protocols in addressing complex reproductive disorders and improving ovarian function.
Secondary Infertility, Anti-Mullerian Hormone, Endocrine Dysfunction, Vandhyatva, Putrajeevakadi Yoga Ksheerpaka
Ayurvedic Management of Viruddhaharajanaya Sidhma
Psoriasis is a chronic, immune-mediated inflammatory skin disorder influenced by genetic, environmental, and dietary factors. In Ayurveda, the condition Sidhma often compared with psoriasis due to similarities in symptomatology. This case explores the correlation between psoriasis and Viruddhahara (incompatible diet), along with the influence of environmental stresses, aligning with Ayurvedic pathogenesis. Materials and Methods: Here we report a case of Viruddhaharajanaya sidhma. Patient presented with erythematous, scaly plaques over the trunk and extremities for the last 8 years. The condition diagnosed clinically and histopathological as chronic plaque psoriasis. A detailed dietary and lifestyle history revealed prolonged consumption of incompatible food combinations (tinned juices and curd and meat on daily basis). Patient was assessed using Ayurvedic diagnostic tools, and the condition was correlated with Sidhma as described in classical text. Management included Dipana pacana, Shodhana (Virecana), and followed by Shamana cikitsa. Results: Within three weeks, a significant reduction in itching, scaling, and erythema was observed. The Psoriasis Area Severity Index (PASI) score reduced from 49 to 7.8. The patient was advised to follow pathya (compatible dietary regimen) and avoid Viruddhahara.
Sidhma, Psoriasis, Ayurvedic management, Viruddhahara, Agadatantra, PASI score
A Review on the Garbhasthapana Potential of Shatavari (Asparagus Racemosus Wild.)
Shatavari (Asparagus racemosus Willd.) is one of the most revered herbs in Ayurveda, renowned for its rejuvenative and fertility-enhancing properties. It is classified among the Garbhasthāpana Mahākaṣāya, a group of herbs that support conception and help sustain pregnancy. This review explores Shatavari’s pharmacological, physiological, and clinical potential in Garbhasthāpana (maintenance of pregnancy), based on classical Ayurvedic literature and modern scientific studies. The herb’s Rasayana, Stanya-janana (galactagogue), and Balya (tonic) properties contribute to strengthening the uterus, stabilizing the embryo, and promoting fetal growth. Modern research corroborates these effects, highlighting its phytoestrogenic, adaptogenic, and uterine tonic actions. Thus, Shatavari serves as a bridge between traditional Ayurvedic wisdom and contemporary reproductive healthcare.
Shatavari, Garbhasthāpana, Ayurveda, Pregnancy support, Asparagus racemosus, Phytoestrogen, Uterine tonic
Psychosocial and Health Impacts of Digital Sexual Violence: Bridging Modern Interventions with Ayurveda
Digital Sexual Violence (DSV) has emerged as a pervasive global challenge with the advancement of technology and increased dependence on digital platforms. It includes cyber harassment, non-consensual image sharing, sextortion, online grooming, and deepfake exploitation. From an Ayurvedic standpoint, such violations disturb Manas (mind), Indriyas (senses), and Sattva (mental strength), affecting holistic health. Methods: This paper aims to critically review the prevalence, forms, psychosocial impact, and preventive strategies for DSV, while exploring Ayurvedic insights through Rasayana and Vajikarana principles for resilience and healing. Studies addressing DSV prevalence, psychological consequences, legal frameworks, preventive measures, and Ayurvedic conceptual parallels were included. Classical Ayurvedic texts were also reviewed for references to Sadvritta, Achara Rasayana, and Vajikarana principles relevant to sexual health. Results: Findings highlight a rising prevalence of DSV worldwide, particularly among adolescents and young adults. Consequences include depression, anxiety, post-traumatic stress disorder (PTSD), social isolation, and increased risk of self-harm. Current preventive strategies emphasize legal reforms, digital interventions, and education. Ayurvedic concepts such as Sadvritta (ethical conduct), Achara Rasayana (psychosocial rejuvenation), and Manonigraha (mental discipline) provide unique preventive and rehabilitative insights. Rasayana drugs like Brahmi (Bacopa monnieri), Ashwagandha (Withania somnifera), and Shankhapushpi (Convolvulus pluricaulis) may strengthen mental flexibility and reduce psychological distress. Conclusion: DSV is a complex threat needing comprehensive solutions. Merging modern strategies with Ayurvedic principles offers a holistic approach, emphasizing ethics, psychosocial balance, and mind-body wellness to support survivor well-being and resilience.
Ayurveda, Digital Sexual Violence, Rasayana, Vajikarana, Psychosocial Health
Evaluation of Vanadhanyaka (Eryngium Foetidum Linn.), A Folklore Drug on Mukhadushika (Acne Vulgaris) - An In-Vitro Study
Face is the index of body and mind. It is the general opinion that smooth and glowing skin of face not only enhances the beauty of a person but it also adds self-confidence. In Ayurvedic classics in the context of Kshudra rogas, Mukhadushika is mentioned. Its signs and symptoms are similar to that of acne vulgaris. One of the causative bacteria is Staphylococcus epidermidis. But at present effective medication or preventive measures with less side effects are very few. So, there is a need for one. Vanadhanyaka (Eryngium foetidum Linn.) is one such drug, which is endowed with a property of antibacterial, anti-inflammatory, analgesic and antioxidant. Phytochemical screening of the leaves indicated the presence of flavonoids, polyphenolic compounds, saponin, phytosteroids, triterpenoids, alkaloids, tannins anthraquinones, cardiac glycosides and terpenes. Eryngium foetidum Linn extracts were carried out. The whole plant was used for the in vitro experiment. The aqueous, alcoholic and hexane extract of the trial drug was tested against the Staphylococcus epidermidis bacteria MTCC (Microbial Type Culture Collection and Gene Bank)435. The in-vitro studies to determine the minimum inhibitory concentration was done by micro-broth dilution method and zone of inhibition by Agar well diffusion method. Hexane extract showed better results compare to alcoholic and aqueous extracts.
Vanadhanyaka (Eryngium foetidum Linn.), Kshudrarogas, Mukhadushika (Acne vulgaris), Staphylococcus epidermidis
Add on Effect of Kulatha Yusha and Clinical Yoga Protocol in Vataja Pratishyaya with special reference to Allergic Rhinitis - A Comparative Clinical Trial
Allergic Rhinitis is an IgE mediated immunological response of nasal mucosa to airborne allergens and is characterized by watery nasal discharge, nasal obstruction, sneezing and itching in the nose. The symptoms are closely related with Vātaja Pratiśyāya. Pratiśyāya is one among the Viruddha āhārajanya rōga mentioned by Caraka. Hence dietary modification can be useful in reducing allergic rhinitis symptoms. Kulatha yūṣa is one among the dietary preparations mentioned in Nāsā rōga pratiṣedha adhyāya of Aṣtānga Hṛdaya, and Kulatha yūṣa is indicated in Pīnasa as well. Clinical yoga training is also proven to lower allergic rhinitis symptoms and to improve the quality of life. Considering these factors as improving allergic rhinitis symptoms, the present study is to compare the add on effect of Kulatha yūṣa and clinical yoga protocol in the subjective and objective parameters of participants with allergic rhinitis receiving Haridrā khaṇḍa against the group receiving Haridrā khaṇḍa alone. The subjective parameters in study group showed statistically significant result when compared to control group (p<0.05) but a statistically insignificant result was obtained for objective parameters in the study group when compared with the control group. Hence Kulatha yūṣa and clinical yoga protocol has an add on effect in the subjective parameters of participants receiving Haridrā khaṇḍa when compared to participants receiving Haridrā khaṇḍa alone. Also, Kulatha yūṣa and clinical yoga protocol has no add on effect in the objective parameters of participants receiving Haridrā khaṇḍa when compared to participants receiving Haridrā khaṇḍa alone.
Allergic Rhinitis, Vātaja Pratiśyāya, Kulatha yūṣa
Role of Marma Therapy in Suryavarta: A Single Case Report with special reference to Frontal Sinusitis
Suryavarta is one among the eleven Shiroroga explained in Ayurveda. Acharya Charaka describes Suryavarta as headache that increases at sunrise and reduces gradually by sunset. This headache is predominantly Vata-Pitta Pradhan Urdhwajatrugata Vyadhi. Frontal sinus inflammation correlates clinically with this classical description in many patients. Marma therapy is a unique non-invasive therapeutic approach described in Ayurveda aimed at regulating Prana Vata, balancing Tridosha and restoring normal neurological circulation in Urdhwajatrugata region. A 45-year-old male patient with acute Suryavarta of 1 month duration was treated only with Marma Therapy without internal medicines. Marma therapy was given twice daily on Sthapani, Avarta, Apanga, Shankha, Utksepa, Simanta, Vidhura, and Adhipati Marma points for 1 minute each point for a duration of 30 days. Significant improvement of 90% reduction in headache intensity and associated symptoms such as photophobia, frontal heaviness and morning rise pain was observed at the end of treatment duration. This case demonstrates that Marma Therapy alone can serve as effective primary therapy in Suryavarta and also offers a safe non-pharmacological management for acute sinus type headache disorders.
Suryavarta, Shiroroga, Marma Therapy, Frontal Sinusitis, Shalakya Tantra, Ayurveda
A Comparative Study to Establish the Effect of Go-Ghrita, Panchatikta Ghrita in Asthikshaya Janya Vata Vriddhi w.s.r. to Osteopenia
Osteopenia (Low bone mass) is the most prevalent condition, and a major cause for Osteoporosis. This may lead to weak and fragile bones and increase the risk of fracture. Around 33.6 million individuals over the age 50 have low bone mass of the hip and thus are at risk of osteoporosis and other complications. In Ayurveda, it can be correlated with Asthi kshaya and it is a condition of degenerative changes in Asthi along with simultaneous vitiation of Vata Dosha residing in Asthi Dhatu occurs. Being a degenerative Vata disorder Asthikshaya (Osteopenia) demands a pioneer treatment of Vata Dosha. Ayurveda gives more weightage to treating this condition, with Snigdh dravya chikitsa. So, considering all these points the study entitled, “A Comparative Study to Establish the Effect of Go-Ghrita, Panchatikta Ghrita in Asthikshaya Janya Vata Vriddhi w.s.r. to Osteopenia”.
Asthi Dhatu, Vata Dosha, Aashraya Ashraye Bhava, Asthi Dhatu Kshaya, Vata Vriddhi, Ghrita
Panchakarma Based Therapeutic Interventions in GNE Myopathy- Insights Through A Case Study
GNE myopathy is a rare autosomal recessive muscular disorder characterized by progressive skeletal muscle atrophy, primarily due to mutations in the GNE gene. In Ayurvedic perspective, this condition is categorized as an Adibala Pravrutta Vyadhi, where Dushti in Beejabhaga Avayava is considered the underlying pathogenic factor. This case study aims to evaluate the efficacy of a comprehensive Panchakarma protocol in improving muscle strength, functional mobility, and overall quality of life in a patient with GNE myopathy. Methods: A 29-year-old female patient, diagnosed with GNE myopathy, presented with bilateral lower limb weakness, difficulty in walking, and impaired ability to rise from a squatting position. The patient underwent an integrative Panchakarma management protocol, which included Sarvanga Abhyanga, Dashamoola Kashaya Seka, Shashtika Shali Pinda Sweda, Mustadi Yapana Basti, Anuvasana Basti with Brihat Chagaladi Ghrita. The therapeutic focus was on Amaharana, Srotoshodhana and Brimhana, aiming to restore systemic balance and muscle function. Results: Post-intervention, the patient demonstrated significant clinical improvement. Objective assessments revealed enhanced lower limb muscle strength, improved ability to walk independently, increased confidence in climbing stairs, and a notable improvement in the GNE Myopathy Functional Activity Score (GNEM-FAS). Subjective reports indicated better overall well-being and functional capacity. Discussion: This case highlights the potential role of Panchakarma therapies in the multidisciplinary management of GNE myopathy. The combined approach of Srotoshodhana and Brimhana may contribute to symptomatic relief and functional enhancement by improving microcirculation, reducing muscle wasting, and promoting systemic nourishment. Conclusion: Therefore, this case study highlights the potential of Panchakarma in improving the quality of life in such rare genetic disorders.
GNE myopathy, Adibala pravrutta Vyadhi, Mustadi Yapana Basti, Brihmana
Evidence Based Ayurvedic Approach in the Management of Dysfunctional Uterine Bleeding
Abnormal uterine bleeding without intrinsic pathology is the hallmark of Dysfunctional Uterine Bleeding (DUB), a frequent gynaecological issue. Because of the vitiation of the Vata and Pitta Doshas, which affects the Artava Vaha Srotas, Ayurveda associates these diseases with Asrigdara or Raktapradara. Main Clinical Finding: A 37-year-old female patient presented with ultrasonography (USG) suggestive of Thickened endometrium with polycystic ovaries. The case was treated for 3 months with a combination of different Ayurvedic drugs to reduce symptoms and cure DUB. Diagnosis: The patient consulted the Ayurvedic OPD of M.M.M. Govt. Ayurveda College & Hospital Udaipur, with the complaint of heavy and prolonged menstrual bleeding, short cycle and generalised weakness since last 4 months. Her USG revealed thickened endometrium with polycystic ovaries and CBC revealed low haemoglobin. Interventions: This DUB patient received treatment with traditional Ayurvedic formulations, such as Shunthyadi churna taken orally and Matra basti with Shatavari Taila 60ml in follicular phase for three consecutive menstrual cycles with addition of Pathya-Apathya. Outcome: Investigations conducted after therapy revealed improvements in hemoglobin levels, endometrial thickness and clinical outcomes. Conclusion: This case demonstrates the potential of Ayurvedic therapy in managing DUB without hormonal intervention.
Asrigdara, Dysfunctional Uterine Bleeding, Shunthyadi Churna, Shatavari Taila, Matra Basti, Menorrhagia
Rasayan Tantra is one of the most important branches of Ayurveda. It helps to delay the ageing process, helps to provide good strength and offer excellent immunity from various infections. It also maintains good digestion, metabolism, cardiac and mental health. Rasayan science also deals with measures, medicines, treatments which bring about delay in ageing process and also helps in the maintenance of health in old age, apart from providing strength and immunity. Rasayan help in the formation of best quality Dhatus/tissues and also support the channels which help in the formation and transportation of tissues and also the nutrition needed to form these tissues from one place of the body to the other. These medicines delay the ageing process by reducing the oxidative stress in the cells of body and central nervous system, thereby promoting the longevity and disease-free body. Rasayana have broad spectrum role as they are anti-inflammatory, anti-cancer, hepatoprotective, renoprotective, neuroprotective, cardiotoic and are excellent immunomodulators. They can be co-related with anti-oxidants in Western Medicine.
Rasayana, Antioxidants, Immunity, Dhatu pushti, Longevity
Clinical Efficacy of Bhoonimbadi Kadha (Decoction) in the Management of Amlapitta
Amlapitta is one of the disturbing illnesses of the developing world. It usually affects people of all age groups. Modern day lifestyle and urbanization strongly affected the dietary habits of upper and lower middle-class people. Due of the indulgence of faulty foods in diet, half cooked foods, exposure to Helicobacter pylori infection, not eating foods at regular intervals, eating during indigestion, not taking enough sleep, etc. are the few causes that reduce the digestive fire causing toxins or acid to accumulate and increase the level of gases in the stomach causing the disease Amlapitta. The signs and symptoms of Amlapitta are similar to gastritis in modern medicine. The conventional treatment for gastritis starts with the use of proton pump inhibitors and H2 receptor blockers. But due to the side effects like headache, constipation, dizziness etc. patients usually fail to continue medicines for adequate relief. In these situations, Ayurvedic medicines have an edge over western medicines as herbal medicines have good gastrointestinal tolerance with least side effects. In this single clinical study, 30 patients were taken having Amlapitta and treated with 20ml twice daily dose of Bhoonimadi kadha before meals with equal quantity of warm water for 60 days. At the end of the study, it is seen that Shamana Chikitsa with Bhoonimadi kadha has shown remarkable improvement with complete relief in burning sensation and pain abdomen.
Amlapitta, Hyperacidity, Pitta, Amavisha, Lifestyle Disorder
Ayurvedic Management of Infertility due to Polycytic Ovarian Syndrome
Ayurveda is the science which not only deals with treating the diseases but also aims to prevention of the various diseases. Curing a diseased person and redefining his healthy status, is a primary goal of a physician. Ayurveda provides valuable guidance on how to maintain a healthy lifestyle and avoid harmful habits, while also offering detailed principles for the diagnosis and treatment of various diseases. Infertility has been one of the unsolved major complaints of womanhood. Infertility impacts approximately one out of every seven couples in their reproductive years and is frequently associated with significant emotional and psychological stress. Infertility is defined as inability to conceive even after one year under normal marital relation without conception. In Ayurveda, this condition is considered as Vandhyatva. According to Ayurveda important factors for conception are considered as Ritu, Kshetra, Ambu and Bija. Disturbance in the normal functioning of Vayu or any imbalance in the Shatbhavas can lead to the condition known as Vandhyatva Also these days most important cause for infertility was PCOS. The condition is managed through Shodhana (purification therapy), Shamana Chikitsa (palliative treatment), and by following an appropriate Dincharya (daily routine). Shodhana is very important in Vandhyatva. Shodhana helps to release Avarodha of vitiated Vayu and provides area for Garbha Utpatti.
Ayurvedic Insights in the Clinical Management of Paget’s Disease
Paget’s disease of bone is a chronic metabolic bone disorder characterized by abnormal bone remodelling, leading to pain, deformity, and increased fracture risk. In Ayurveda, it can be studied under the heading of Asthi Dhatu Kshaya and vitiation of Vata dosha, requiring holistic management to restore balance and improve bone health. This case study explores the Ayurvedic therapeutic approach involving Sarvanga Abhyanga, Parisheka, and Tikta Ksheera Basti for managing Paget’s disease symptoms. These interventions aim to pacify Vata dosha, nourish the Asthi dhatu, reduce pain and inflammation, and enhance overall musculoskeletal function. The combined Panchakarma therapies demonstrated significant symptomatic relief and improvement in the patient's quality of life, suggesting a promising integrative treatment protocol for Paget’s disease management in Ayurveda.
Paget’s disease Asthi Dhatu Kshaya Vata dosha Osteitis deformans
Interrelationship Between Sleep Disorders and Early Presbyopia: Ayurvedic Insights into Preventive Care
Presbyopia, traditionally considered an inevitable consequence of aging, is now increasingly observed in younger individuals, driven by modern lifestyle stressors such as screen overuse, psychological strain, and irregular sleeping patterns. Ayurveda echoes these findings, identifying Swapna Viparyaya (irregular sleeping pattern) as a primary Nidana (causative factor) Netra Roga (ocular disorders). Objective: To explore the connection between poor sleep quality and early-onset presbyopia through an integrative- merging modern ocular physiology with Ayurvedic preventive strategies. Methods: This analysis was conducted through classical Ayurvedic texts like Charak Samhita and Ashtanga Hridaya. Both contemporary clinical insights and historical perspectives from traditional medicine were examined to provide a comprehensive understanding of the topic. Discussion: Scientific evidence underscores the role of circadian rhythms in regulating the redox state of the lens, with key elements such as Bmal1 gene expression, aqueous humour secretion, and glutathione transport closely linked to sleep-wake cycles. Sleep deprivation leads to impaired blood flow, oxidative stress, and cellular degeneration in ocular tissues. Ayurveda offers neuro-restorative therapies- Shirodhara, Abhyanga, and Shiropich- which help regulate the hypothalamic-pituitary-adrenal axis, improve melatonin synthesis. When combined with good sleep hygiene practices, these interventions promote redox homeostasis and delay presbyopic changes. Conclusion: Both modern science and Ayurvedic principles recognize poor sleep quality as one of the causative factors for pre onset of presbyopia. Integrating sleep hygiene with classical Ayurvedic regime for quality sleep presents a holistic and evidence-aligned approach to delay the onset of presbyopia. This integrative model holds global relevance in preventive ophthalmology.
Presbyopia, Circadian Rhythm, Oxidative Stress, Shirodhara, Shiropichu, Abhyang, Swapna Viparyaya
Yakrut Karma in Post-Covid Sequelae: An Integrative Review
Post-COVID syndrome presents with a wide range of persistent symptoms, including fever, fatigue, hypertension, anorexia, digestive ailments, body aches, nausea, and malnutrition. According to Ayurveda, all these manifestations closely resemble the classical symptoms of Rasa Dhatu Dushti. When the quality of Rasa is compromised, its successive transformation into Rakta Dhatu is hindered, predisposing to disturbances in the blood tissue and related metabolic domains, with the Yakrut presenting as the primary site of dysfunction. This review analyses post-COVID sequelae in the framework of Yakrut Karma and Rasa–Rakta Dhatu Dushti, investigating how persistent changes in Rasa Dushti after COVID can result in underlying Rakta Dushti, which ultimately presents as liver damage. Modern clinical findings such as higher liver enzyme levels, metabolic disturbances, and persistent inflammation correlate with the Ayurvedic overview of impaired Yakrut Karma, indicating altered liver function and metabolism. An effort has been undertaken to connect recent scientific evidence with traditional interpretations of Dhatu imbalance, highlighting the importance of Ayurveda in assessing liver health following COVID-19.
Rasa Rakta Dushti, Yakrut Karma, Long COVID, Liver health
Biometric Correlation of the Vrana Ropana in Sushruta Samhita: An Integrating Ayurvedic Principles of Vrana Ropana with Modern Regenerative Wound Healing
Wound healing is a fundamental physiological process aimed at restoring structural and functional tissue integrity. Despite advances in modern therapies, chronic and non-healing wounds continue to pose a substantial global health burden. Regenerative medicine- through stem cells, engineered biomaterials, and biological signalling- has introduced novel approaches, yet their clinical translation remains limited by costs, technical complexity, and inconsistent outcomes. Ayurveda, particularly the Shalya Tantra tradition of Sushruta, presents a structured, biology-aligned framework for wound management based on sequential Shodhana (cleansing), Ropana (tissue regeneration), and Purana/Sandhana (structural restoration). This review analyzes the biometric correlation between Sushruta’s Vrana Ropana principles and modern regenerative wound biology, proposing an integrative model that combines traditional Ayurvedic therapeutics with contemporary bioengineering. Such convergence offers pathways to develop biomimetic, cost-effective, and stage-specific wound-care strategies.
Vrana ropana, Regenerative medicine, Wound healing, Biomimetic integration, Sushruta
Role of Shunthi Bilva Kwatha with Yava Saktu in Garbhini Chhardi (Emesis Gravidarum)
Garbhini Chhardi, or pregnancy related nausea and vomiting, is a common problem that causes discomfort, dehydration, and digestive issues in many pregnant women. This article discusses how Shunthi bilva kwatha with Yava saktu can help manage this condition through an Ayurvedic approach Zingiber officinaleis (dry ginger) and Aegle marmelos (Bilva) known for its Vata-balancing, digestive-stimulating, and appetite-improving properties. These actions help regulate Vata dosha, support the digestive system, increases the Agni and reduce feelings of nausea. Hordeum vulgare (roasted barley) has thirst-relieving and Kapha-reducing qualities. It helps control excessive thirst and balances Kapha, both of which are commonly linked to nausea and vomiting during pregnancy. The article highlights how these two ingredients work together to give better relief from Garbhini Chhardi (vomiting during pregnancy). Their combined effect helps tackle the root causes by supporting digestion, balancing the Doshas and keeping the body hydrated. Because of this, the remedy helps reduce both how often vomiting happens and how strong it feels. Along with that, this mixture is easy to take and fits well into the busy routine of today’s expecting mothers. Overall, this Ayurvedic combination offers a safe, natural, and effective way to manage pregnancy-related vomiting, helping ensure comfort and well-being for both the mother and the baby In Ayurveda Acharyas have advised that the patient’s provided numerous formulations for addressing Garbhini Chhardi This study evaluates the effectiveness of Shunthi Bilwa Kwath Combined with Yava Saktu in managing this condition.
Garbhini Chhardi, Emesis Gravidarum, Shunthi Bilva Kwatha with Yava Saktu, Vyakta Garbha Lakshana.
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Driving Meaningful Change for Cohesive Grasp of Breast Carcinoma Through Integrative Ayurvedic Principles
Breast carcinoma is the most prevalent malignancy among women worldwide, accounting for nearly one-fourth of all female cancers. It remains a leading cause of cancer-related mortality, particularly in developing countries. Objective: To review the epidemiological, pathological, diagnostic, and therapeutic aspects of breast carcinoma and to explore the integrative potential of Ayurvedic principles, particularly Sthana Arbuda, in its management. Methods: An extensive literature review was conducted using databases such as PubMed, WHO reports, AYUSH Research Portal, and classical Ayurvedic texts including Charaka Samhita, Sushruta Samhita and Bhavaprakasha. The focus was on publications from 2010–2024 discussing breast carcinoma, its subtypes, current treatment modalities and Ayurvedic interventions. Results: Breast carcinoma exhibits significant heterogeneity in clinical behaviour and prognosis. Molecular classification- Luminal A, Luminal B, HER2-enriched, and Triple Negative- guides current treatment strategies. Conventional management involves surgery, chemotherapy, radiotherapy, hormonal and targeted therapy. Ayurvedic literature correlates breast carcinoma with Sthana Arbuda, attributing it to Tridosha imbalance and Mamsa–Rakta–Meda vitiation. Ayurvedic management emphasizes Shodhana (purification), Shamana (palliative therapy), and Rasayana (rejuvenation) approaches using formulations such as Kanchanara Guggulu, Varunadi Kashaya, Shivagutika, Guduchi, and Ashwagandha. Integrative approaches show potential for symptom relief, enhanced immunity, minimize recurrence and improves quality of life. Conclusion: Early detection, personalized multimodal therapy, and integration of Ayurvedic Rasayana principles may enhance treatment outcomes and minimize recurrence in breast carcinoma. Further clinical and translational research is warranted to validate the synergistic role of Ayurvedic interventions alongside modern oncology.
Breast carcinoma, Sthana Arbuda, Rasayana, Integrative oncology, Tridosha
A Comparative Study on the Phyto-Acoustic Influence of Mantras on Seed Germination and Early Plant Development
Sound-based plant stimulation is recognized as a novel tool in agricultural biotechnology. Vrikshayurveda, the ancient Indian science of plant life, describes the use of mantras and vibrational practices to enhance seed vitality, germination, and crop productivity. This study investigates the scientific validity of mantra-induced phyto-acoustic modulation on germination and early vegetative growth of Trigonella foenum-graecum (Methika). Objectives: To assess the impact of daily exposure to two Sanskrit mantras- Om Sri Matre Namah and Dakshinamurthy Gayatri Mantra- on germination rate, sprouting time, root and shoot elongation, and overall plant vigor. Methods: Forty seeds were divided into a control group (n=20) and an experimental mantra-exposed group (n=20). The experimental group received one hour of mantra exposure (108 repetitions each) daily for 15 days under controlled environmental conditions. Quantitative and qualitative growth parameters were recorded and analyzed. Results: Mantra exposure significantly accelerated germination, reduced sprouting time, and produced greater shoot (5.5–6 cm vs. 2–3 cm) and root length (4.5–5 cm vs. ~2 cm) compared to controls. Plants in the experimental group demonstrated superior morphological uniformity, better root architecture, and enhanced foliage density. Conclusion: Mantras serve as effective phyto-acoustic stimulants capable of enhancing early plant development. Findings support the principles of Vrikshayurveda, which recognize sound, intention, and vibrational influences as modulators of plant vitality. This study strengthens the scientific foundation for integrating acoustic and Vrikshayurvedic practices into sustainable agriculture.
Vrikshayurveda, Plant life, Phyto-acoustic modulation, Mantra, Germination
Ayurvedic Management of Ankylosing Spondylitis
Ankylosing Spondylitis (AS) is a chronic inflammatory condition primarily affecting the spine, leading to stiffness, pain, and restricted mobility, its impact on quality of life can be significant. This case report presents the management of a 20-year-old male diagnosed with ankylosing spondylitis, who presented with stiffness, pain, and restricted range of motion of the back. The patient was treated on the line of treatment of Vatavyadhi with a combination of Ayurvedic therapies including Prushtha dhara (pouring a stream of medicated oil over spine), Patrapinda swedana (Pottali sudation with medicated leaves), Matra basti (enema with medicated oil) and Shaman Aushadh (palliative treatment) alleviating the Vata Dosha. Significant relief was observed, evidenced by the Schober's test turning negative and a substantial improvement in spinal flexion. While this case study offers encouraging results, further research through more case reports and planned clinical trials is warranted to establish the efficacy of Ayurvedic approaches in managing Ankylosing Spondylitis.
Ankylosing Spondylitis, Basti, Prushtha dhara, Patrapinda swedana, Range of Motion, Vatavyadhi
Ayurvedic Management of Chronic Sinusitis with Correlation to Vata Kaphaja Pratishaya
Sinusitis is a chronic inflammatory condition of the paranasal sinuses that is associated with nasal obstruction, frontal headache, and mucopurulent discharge. In Ayurveda, this condition closely resembles Kaphaja Pratishaya, caused by the vitiation of Kapha and Vata Doshas, obstructing Pranavaha Strotas. Aim: To evaluate the efficacy of Ayurvedic management in a diagnosed case of chronic sinusitis (Kaphaja Pratishaya). Material and Methods: A single clinical case of a 51-year-old female patient with chronic sinusitis and nasal polyp (Nasarsha) was treated with internal and external Ayurvedic therapies for eight weeks. The regimen included Pratimarsha Nasya Karma with IAFA Nasal All Clear X Drops and Nasa Yoga Grutham, internal administration of Aahar Amrutham Ras, Pitpapra Capsules, IAFA Respiratory Detox Tablets, Sitopaladi Churna, Respiro Detox Formula, and Haridrakhandam, along with dietary regulation and Pranayama. Clinical assessment was done before, during, and after treatment. Results: Significant reduction in nasal obstruction, frontal headache, snoring, and mucus discharge was observed after four weeks, with complete remission by eight weeks. The patient reported improved olfactory function, restful sleep, and no recurrence after exposure to cold or allergens. Conclusion: The Ayurvedic approach focusing on Kapha-Vata Shamana, Srotoshodhana, and Rasayana principles effectively managed chronic sinusitis. This case report of sinusitis correlated with Kaphaja Pratishaya highlights Ayurveda’s treatment potential in chronic respiratory disorders.
Chronic Sinusitis, Kaphaja Pratishaya, Nasya Karma, Pranavaha Strotas, Kapha-Vata Dushti, IAFA treatment, Nasa Yoga Grutham.
Contemporary and Ayurvedic Therapeutic Strategies in Colorectal Cancer: A Systematic Review
Colorectal cancer (CRC) remains one of the most prevalent malignancies worldwide, contributing significantly to cancer-related morbidity and mortality. Although survival rates have increased because of modern therapeutic approaches such surgery, chemotherapy, radiation, targeted therapy, and immunotherapy, but problems like toxicity, expense, resistance, and recurrence still exist. At the same time, Ayurvedic treatment provides a comprehensive framework that emphasizes herbal remedies, nutrition, lifestyle, Dosha balance, and detoxification (Panchakarma). The mechanical justification, preventative and supporting functions, and integrative care prospects of contemporary and Ayurvedic approaches to CRC management are all examined in this systematic review. In order to maximize patient outcomes, the review emphasizes the significance of fusing traditional Ayurvedic principles with evidence-based modern oncology.
Colorectal Cancer, Ayurveda Medicines, Integrative Oncology, Phytochemicals, Chemotherapy Toxicity, Targeted Therapy.