An Open Randomized Comparative Clinical Study on the Effect of Shiva Guggulu and Vatari Guggulu along with Kottamchukkadi Lepa in Amavata

Abstract

Rheumatoid Arthritis (Amavata) is an autoimmune seditious complaint that causes pain, swelling, stiffness, destruction and functional disability in the affected joints. It's defined as a habitual multisystem complaint characterized by patient seditious synovitis, generally involving supplemental joints in a symmetric distribution with eventuality to beget cartilage destruction and bone attritions. According to Ayurveda, the main cause of the complaint is conformation of Ama due to Agnimandya. Even though many researches has been done in Amavata management, there is still huge scope to explore new course of action. Here we tried the formulation to treat Amavata according to Ayurvedic classics. To evaluate the effect of Shiva guggulu along with Kottamchukkadi lepa and Vatari gugggulu along with Kottamchukkadi lepa in the management of Amavata. 60 patients who were diagnosed with Amavata were allocated randomly in two groups. The trial drug Shiva guggulu 2gram TID after food with lukewarm water as Anupana along with application of Kottamchukkadi lepa was given to 30 patients of group A and Vatari guggulu in the dosage of 1gram TID after food with lukewarm water as Anupana along with application of Kottamchukkadi lepa was given to 30 patients of group B for duration of 30 days.