Driving Meaningful Change for Cohesive Grasp of Breast Carcinoma Through Integrative Ayurvedic Principles

Abstract

Breast carcinoma is the most prevalent malignancy among women worldwide, accounting for nearly one-fourth of all female cancers. It remains a leading cause of cancer-related mortality, particularly in developing countries. Objective: To review the epidemiological, pathological, diagnostic, and therapeutic aspects of breast carcinoma and to explore the integrative potential of Ayurvedic principles, particularly Sthana Arbuda, in its management. Methods: An extensive literature review was conducted using databases such as PubMed, WHO reports, AYUSH Research Portal, and classical Ayurvedic texts including Charaka Samhita, Sushruta Samhita and Bhavaprakasha. The focus was on publications from 2010–2024 discussing breast carcinoma, its subtypes, current treatment modalities and Ayurvedic interventions. Results: Breast carcinoma exhibits significant heterogeneity in clinical behaviour and prognosis. Molecular classification- Luminal A, Luminal B, HER2-enriched, and Triple Negative- guides current treatment strategies. Conventional management involves surgery, chemotherapy, radiotherapy, hormonal and targeted therapy. Ayurvedic literature correlates breast carcinoma with Sthana Arbuda, attributing it to Tridosha imbalance and Mamsa–Rakta–Meda vitiation. Ayurvedic management emphasizes Shodhana (purification), Shamana (palliative therapy), and Rasayana (rejuvenation) approaches using formulations such as Kanchanara Guggulu, Varunadi Kashaya, Shivagutika, Guduchi, and Ashwagandha. Integrative approaches show potential for symptom relief, enhanced immunity, minimize recurrence and improves quality of life. Conclusion: Early detection, personalized multimodal therapy, and integration of Ayurvedic Rasayana principles may enhance treatment outcomes and minimize recurrence in breast carcinoma. Further clinical and translational research is warranted to validate the synergistic role of Ayurvedic interventions alongside modern oncology.