Biometric Correlation of the Vrana Ropana in Sushruta Samhita: An Integrating Ayurvedic Principles of Vrana Ropana with Modern Regenerative Wound Healing

Abstract

Wound healing is a fundamental physiological process aimed at restoring structural and functional tissue integrity. Despite advances in modern therapies, chronic and non-healing wounds continue to pose a substantial global health burden. Regenerative medicine- through stem cells, engineered biomaterials, and biological signalling- has introduced novel approaches, yet their clinical translation remains limited by costs, technical complexity, and inconsistent outcomes. Ayurveda, particularly the Shalya Tantra tradition of Sushruta, presents a structured, biology-aligned framework for wound management based on sequential Shodhana (cleansing), Ropana (tissue regeneration), and Purana/Sandhana (structural restoration). This review analyzes the biometric correlation between Sushruta’s Vrana Ropana principles and modern regenerative wound biology, proposing an integrative model that combines traditional Ayurvedic therapeutics with contemporary bioengineering. Such convergence offers pathways to develop biomimetic, cost-effective, and stage-specific wound-care strategies.