Pharmaceutical and Analytical Standardisation of Khanda Shunthi Avaleha

Abstract

Background: To assure the therapeutic efficacy and safety of Ayurvedic formulation it is demand of time to standardise the Ayurvedic medicines. Khanda Sunthi Avaleha is Ayurvedic formulation used for the treatment of Aamvata described in Bhavprakasha Samhita. The present study was aimed that to standardise the Khanda Shunthi Avaleha by using the various testing parameters. Methods: Raw material used to prepare Khanda Shunthi Avaleha was procured from reliable sources, identified and authenticated by using different parameters as per API. Total 8 batches of Avaleha were prepared, different observations were noted down and finally analytical study of Khanda Shunthi Avaleha was carried out by using the. organoleptic characters, physico-chemical parameters. Other specified test like heavy metal test, microbial test, aflatoxins, pesticide residue, HPTLC etc. Result: Raw material was of standard quality which was used to prepare the Khanda Shunthi Avaleha. All 8 batches of Khanda Shunthi Avaleha has passed the confirmatory test of Avaleha. Organoleptic characters of all the batches were found similar. The findings of analytical parameter testing of Avaleha were within the limit as per the standards of Ayurvedic formulations mentioned in API. Conclusion: Current method followed for the preparation of Khanda Shunthi Avaleha can be considered as standard operative procedure in further studies and the test result obtained would serve as the tools for assistance to the scientific organisations, regulatory bodies and manufacturer for developing standard formulation of great efficacy.