Lashuna Rasayana in Stree Vandhyatva (Female Infertility): A Narrative Review

Abstract

Stree vandhyatva (female infertility) is a complex clinical condition described in Ayurveda as resulting from derangement of Doshas, impairment of Agni, obstruction of Srotas, and qualitative or quantitative defects of Artava and Shukra. Rasayana therapy is advocated to rejuvenate reproductive tissues and enhance fertility potential. Lashuna (Allium sativum Linn.), widely used as both food and medicine, is described in classical Ayurvedic texts as a potent Rasayana, Vrushya, Balya, and Srotoshodhaka drug. Lashuna Rasayana has traditionally been employed in various gynaecological disorders, including infertility. Contemporary scientific studies demonstrate antioxidant, anti-inflammatory, insulin-sensitizing, antimicrobial, and hormonal modulatory properties of garlic, which are relevant to the etiopathogenesis of female infertility, particularly in conditions such as polycystic ovary syndrome (PCOS), oxidative stress–related ovarian dysfunction, and chronic inflammation. Experimental studies reveal protective effects on ovarian tissue and modulation of reproductive hormones, while limited clinical studies suggest improvement in metabolic and endocrine parameters associated with infertility. This narrative review explores the Ayurvedic rationale, pharmacological properties, experimental and clinical evidence, and safety considerations of Lashuna Rasayana in Stree vandhyatva. Although the available evidence is encouraging, further well-designed clinical trials with fertility-specific outcomes are necessary to establish its definitive therapeutic role.