Pharmacological and Clinical Efficacy of Patoladi Kwatha in the Management of Amlapitta

Abstract

Global Gastro-intestinal tract disorders increased by 67-74% between 1990 and 2019, which might be due to ageing populations. Functional disorders have a prevalence of 25-32%, with regional variation and a higher rate in Asia. In Ayurveda, vitiation of Pitta causes Amlapitta Vyadhi (acid peptic diseases), which is divided based on the movement of pathological doshas, i.e., Adhog amlapitta and Urdhvag amlapitta. In Urdhvag amlapitta, there is an increase in the Drava guna of Pitta dosha, which transforms Pitta’s prakrut katu rasa into Virkut amla rasa. In Ahara pachana (digestion of ingested food), there is involvement of Pachak pitta, Kledaka kapha, and Saman vayu. For proper digestion, there must be a balance among all three. Pachak pitta plays a major role in digestion. Hetu sevana (causative factors) causes Tridosha-Prakopa, particularly when the Amla and Drava guna of Pitta increase. It causes Agnimandya (weak digestive fire), which in turn causes Vidagdha awastha of Pitta, leading to Amlapitta Vyadhi. People who dwell in marshy or humid surroundings are more likely to suffer from Amlapitta (acid peptic illnesses), according to Kashyap Acharya. Here Patoladi kwatha contains Trichosanthes dioica, Azadirachta indica A. Juss., Terminalia chebula Retz, Terminalia bellerica Roxb. and Emblica officinalis Gaerth. is described as a powerful treatment for managing Amlapitta by balancing the body’s Pitta and Kapha doshas in the Ayurvedic text – Yogratnakar Adhyaya on Amlapitta. In the present review, an attempt has been made to understand the probable mechanism of action of Patoladi Kwatha in Amlapitta management.