A Clinical Evaluation of Oral and External Use of Siddharthakadi Agada in Dadru Kustha

Abstract

Skin plays a crucial role in protection from the environmental hazards and infections such as bacterial, viral, fungal and harmful UV rays. Conditions like psoriasis, eczema and fungal infections such as Dadru (ringworm) can cause psychological distress and social withdrawal. Following the classical knowledge, Siddharthakadi Agad from the Charaka Samhita was selected as the intervention drug. AIM & OBJECTIVES: - To evaluate the clinical efficacy of Siddharthakadi Agad in Dadru Kushtha and to provide reliable, safe and cost-effective treatment. Materials and Methods: Total 40 patients were registered irrespective of age, gender, religion, occupation etc, from the OPD of PG Department of Agadtantra Rishikul Campus Hospital, Haridwar. Type of study was Single Arm Clinical Study. Total duration of study was 60 days. The dose of Siddharthakadi Agad Vati was 2 tablets after meal and Siddharthakadi Agad Lepa was applied externally. Statistical analysis: For comparison of subjective and objective criteria within same group Wilcoxon sign rank test and Paired t-test respectively were applied before and after the treatment. Result: Siddharthakadi Agad preparation was found to be effective against all the clinical symptoms of Dadru Kushtha. After analysing the data, 36 patients statistically showed highly significant improvement in all the symptoms. Conclusion: Siddharthakadi Agad Gutika and Lepa exhibit antifungal, anti-inflammatory, antioxidant, antimicrobial, anti-allergic, anti-pruritic and immunomodulating properties which collectively reduced inflammation, resolved raised patches and enhanced immunity. The results indicates that treatment based on Ayurvedic principles when administered with appropriate dosage, duration and strict adherence to Pathya and Apathya Ahara leads to successful outcomes in cases of Dadru kustha.