A Comparative Clinical Study to Evaluate the Shodhana and Ropana Effect of Sarjikadya Ghrita Ointment Over Povidone Iodine Ointment in the Management of Dushta Vrana (Chronic Ulcers)

Abstract

The term Vrana refers to “Vrana Gatra Vichūrṇane” meaning disruption or disintegration of body tissues. When a Vrana exists in a Duṣṭa Avasthā, it does not heal spontaneously; therefore, Vrana Śodhana followed by Vrana Ropaṇa is essential for its management. Clinically, it can be correlated to chronic ulcers based on the Lakṣaṇas described by the Āchāryas. According to the World Health Organization, nearly 80% of the global population depends on traditional medicine for primary healthcare needs. Classical Ayurvedic treatments for wound management, as mentioned in Suśruta Saṃhitā particularly the Ṣhaṣṭi Upakrama offer effective approaches for Duṣṭa Vrana management. Among these, the application of Ghṛita is one important and beneficial method for promoting wound healing. Objectives: To compare the efficacy of Sarjikadya Ghrita ointment over povidone iodine ointment in the management of Dushta vrana. Materials & Methods: Clinically diagnosed 40 patients of Dushta Vrana were selected from IPD and OPD of SJGAMC&H and randomly assigned into two groups with 20 patients in each group. Group A- trial group was treated with Sarjikadya Ghrita Ointment application and group B- control group was treated with Povidone Iodine ointment application. Results: The study results revealed that both interventions produced significant results but control group delivered slightly better outcome over trial group. Conclusion: All 40 patients diagnosed with Dushta Vrana were randomly divided in Group A and Group B and subjected to application of Sarjikadya ghrita ointment group A and povidone iodine ointment group B respectively.