Pharmaceutical Preparation, Analytical Evaluation and Quality Standardization of Lakshadi Taila and its Modified Dosage Form Lotion

Abstract

Lakshadi Taila is a classical Ayurvedic medicated oil traditionally used in the management of various dermatological conditions such as wounds, itching, inflammation, and discoloration of the skin. The formulation contains Laksha along with several medicinal herbs processed in sesame oil according to the principles of Sneha Kalpana. Aim and Objectives: To carry out the pharmaceutical preparation, analytical evaluation, and quality standardization of Lakshadi Taila and to develop its modified dosage form as a lotion for improved applicability and patient compliance. Materials and Methods: Lakshadi Taila was prepared according to the classical Sneha Kalpana method using authenticated raw drugs. Five batches of the formulation were prepared under identical conditions to ensure reproducibility. The prepared samples were subjected to organoleptic and physicochemical evaluation including parameters such as color, odor, specific gravity, refractive index, acid value, saponification value, peroxide value, and iodine value. Microbial analysis and phytochemical screening were also carried out. Further, a modified dosage form in the form of lotion was developed from the prepared Lakshadi Taila and evaluated for its pharmaceutical characteristics. Results: All five batches of Lakshadi Taila showed comparable organoleptic and physicochemical parameters, indicating uniformity and consistency in preparation. The analytical results were found to be within acceptable limits. The developed lotion exhibited satisfactory consistency, stability, and ease of application. Conclusion: The study established the pharmaceutical preparation and analytical standards for Lakshadi Taila and demonstrated the feasibility of developing a modified dosage form lotion, which may enhance patient compliance and therapeutic applicability.