A COMPARATIVE STUDY OF THERAPEUTIC EFFECT OF NEEM (AZADIRACHTA INDICA A.JUSS.) AND HARIDRA (CURCUMA LONGA LINN) IN THE MANAGEMENT OF WOUND HEALING

Abstract

Wound is simply a disruption of any tissues: soft tissue or bone or internal organs. Wound may be produced by physical, chemical, thermal, microbial or immunological insult to the tissue. It is common problems from ancient time. Although wound healing is a natural restorative response to any kind of tissue injury but due to bacterial contamination of an open wound delays the process of healing. In Ayurveda the term used for wound is Vrana. In this study Neem and Haridra was taken which has been mentioned in Ayurvedic classics for the treatment of wound. In present clinical study 54 patients with classical signs and symptoms of wound were randomly selected and divided into three groups A, B and C. The fine powder and decoction were prepared from Neem (Azadiracta indica A.Juss.) and Haridra (Curcuma longa Linn). Decoction applied externally for dressing of wound and 3gm. fine powder given orally twice a day according to their group for 30 days. The values of scores of different variables i.e. signs and symptoms recorded before and after the treatment were statistically analyzed. The result showed highly significant decline in the severity of subjective parameters like size, discharge etc. but group C showed better results in size, tenderness and discharge compare to that of group A and B. The study revealed that both drugs have excellent properties to accelerate wound healing but combined forms of two drugs are more potent than using alone.