PHARMACO-THERAPEUTIC STUDY OF NEEM (AZADIRACHTA INDICA A.JUSS.) IN THE MANAGEMENT WOUND HEALING

Abstract

Today in modern era, fast moving life, human being are more prone to injury. Wound is simply a disruption of any tissues: soft tissue or bone or internal organs. Wound may be produced by physical, chemical, thermal, microbial or immunological insult to the tissue. It is common problems from ancient time. Although wound healing is a natural restorative response to any kind of tissue injury but due to bacterial contamination of an open wound delays the process of healing. Therefore the aim of treating a wound is to either shorter the time required for healing or to minimize the undesired consequences. In present study 20 patients with classical signs and symptoms of wound were randomly selected in OPD/IPD of govt. Ayurved Hospital Patna. The fine powder of non woody parts (Leaf, bark of stem and root, flower and fruit) of Neem and decoction of its leaves were prepared. Decoction applied externally for dressing the wound and 3gm. fine powder given orally twice a day for 30 days. The area of wound measured manually by tracing methods. The values of scores of different variables i.e. signs & symptoms recorded before & after the treatment were statistically analyzed. It is observed that the size, pain, tenderness, smell, swelling, discharge, burning sensation, itching sensation and colour of wound all were decreased with statistically highly significant value at the level (P< 0.001). The study shows that Neem having excellent properties to accelerate the wound healing safely.