A Comparative Clinical Evaluation of Triushnadi Vati and Salsaradi Prameha Nashak Yoga in the Management of Madhumeha (Type-2 Diabetes Mellitus)

Abstract

Madhumeha (Type-2 Diabetes Mellitus) is a chronic metabolic disorder characterized by hyperglycemia and classical symptoms such as polyuria, polydipsia, and polyphagia. Ayurvedic formulations like Triushnadi Vati and Salsaradi Prameha Nashak Yoga are widely used, but comparative clinical evidence is limited. Aim: To evaluate and compare the efficacy of Triushnadi Vati, Salsaradi Prameha Nashak Yoga, and their combination in the management of Madhumeha. Materials and Methods: A randomized controlled clinical trial was conducted on 60 patients, of which 57 completed the study. Patients were divided into three groups: Group A (Triushnadi Vati), Group B (Salsaradi Prameha Nashak Yoga), and Group C (combination therapy) for 60 days. Assessment was based on subjective symptoms and objective parameters including FBS, PPBS, and HbA1c. Statistical analysis was performed using paired t-test and ANOVA. Results: Groups B and C showed statistically significant improvement (p<0.01) in both subjective and objective parameters. Group B demonstrated maximum reduction in FBS (18.34%) and PPBS (23.95%), while Group C showed comparable results. Group A showed mild to moderate improvement. HbA1c reduction was significant in all groups. Conclusion: Salsaradi Prameha Nashak Yoga, alone and in combination, showed superior efficacy compared to Triushnadi Vati. Combination therapy provides synergistic benefits and may be effective for long-term management of Madhumeha.