Acute and Subacute Toxicity Study of Abhraka Bhasma- Incinerated Mica Ash

Authors

  • Shyama MD Scholar, Dept. of Ras shastra and Bhaishajya kalpana, NIA, Deemed University, Jaipur, (Raj.), India
  • Sanjay Kumar Associate Professor, Dept. of Ras shastra and Bhaishajya kalpana, NIA, Deemed University, Jaipur, (Raj.), India
  • Sakhitha K.S Assistant Professor, Dept. of Ras shastra and Bhaishajya kalpana, NIA, Deemed University, Jaipur, (Raj.), India
  • Anita Choudhary MD Scholar, Dept. of Ras shastra and Bhaishajya kalpana, NIA, Deemed University, Jaipur, (Raj.), India
  • Pooja Yadav MD Scholar, Dept. of Ras shastra and Bhaishajya kalpana, NIA, Deemed University, Jaipur, (Raj.), India

DOI:

https://doi.org/10.47070/ayushdhara.v10i4.1025

Keywords:

Abhraka Bhasma, Safety, Sub acute toxicity, Incineration

Abstract

Among the various Ras dravyas (mineral drugs), Abhraka Bhasma (incinerated mica ash) is widely used in therapeutics. Many herbal and other organic materials have been quoted in reference for various procedures in preparing Abhraka bhasma. It is wonderful that different pharmacological action has been attributed to different Dravyas used in the pharmaceutical processing of Abhraka Bhasma. However, to establish the safety of such metallic and mineral formulation it is the need of the hour to generate scientific data for such drugs. In the present study two samples of Abhraka Bhasma were prepared using two different methods. The safety profile of Abhraka Bhasma samples (AB-1 & AB-2) were evaluated by conducting acute and subacute toxicity study as per OECD Guidelines. Both acute and sub-acute toxicity study demonstrated safety of AB-1 and AB-2 when administered at therapeutic dose, TED X5 dose and TED X10 dose. Even though the sample AB-1 was prepared using a smaller number of Puta, it was sufficient for preparing good quality of Bhasma and was non-toxic

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Published

28-09-2022

How to Cite

1.
Shyama, Sanjay Kumar, Sakhitha K.S, Anita Choudhary, Pooja Yadav. Acute and Subacute Toxicity Study of Abhraka Bhasma- Incinerated Mica Ash. ayush [Internet]. 2022Sep.28 [cited 2023Jan.30];9(4):18-26. Available from: https://ayushdhara.in/index.php/ayushdhara/article/view/1025

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